Skin Disorders Case

An otherwise healthy 4-week-old infant male is noted to have vesicles and pustules on his palms and soles
Skin Disorders Case

The patient's mother thinks the eruption may be pruritic because the infant is not sleeping well and is constantly rubbing his hands and feet. The mother describes the lesions as "coming in waves." Other members of the family are not itching. 

What is the most likely diagnosis?

A. Acropustulosis of infancy

B. Congenital syphilis

C. Scabies

D. Sucking blisters

E. Contact dermatitis

The correct answer is A. 

The infant has acropustulosis of infancy. Acropustulosis of infancy is a very pruritic eruption on the palms, soles, and lower extremities. 


Question & Explanation: Cabana MD. Rudolph’s Pediatrics, 22e, Self-Assessment and Board Review; 2014. 

Photo: Rudolph CD, Rudolph AM, Lister GE, First LR, Gershon AA. Rudolph's Pediatrics, 22nd ed; 2011.