Coronary Plaque Rupture

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A plaque rupture precipitating acute myocardial infarction or acute coronary syndrome is depicted. Therapeutic interventions dealing with plaque, platelet and thrombus are shown in the blue boxes. ASA, aspirin; IV, intravenous; LMWH, low-molecular-weight heparin; PO, oral; UFH, unfractionated heparin. Adapted with permission from Davies MJ, Thomas AC, Knapman PA, et al: Intramyocardial platelet aggregation in patients with unstable angina suffering sudden ischemic cardiac death. Circulation. 1986 Mar;73(3):418-427.

Read about heart disease in context:

Hurst's the Heart, 14e. Chapter 42. Percutaneous Coronary Interventions in Acute Myocardial Infarction and Acute Coronary Syndromes

Read more about heart disease: 

CURRENT Diagnosis and Treatment: Cardiology, 5e: Chapter 8. Acute Myocardial Infarction

Hurst’s the Heart, 14e. Chapter 108. Women and Heart Disease: An Evolving Saga

Harrison’s Principles of Internal Medicine, 20e. Chapter 268: Non-ST-Segment Elevation Acute Coronary Syndrome (Non-ST-Segment Elevation Myocardial Infarction and Unstable Angina)




Melanie Allison, DNP, MSN, RN, ACNP-BC

Executive Editorial Specialist, McGraw-Hill Education

Melanie Allison is the Executive Manager of Education & Learning with McGraw Hill. She earned her Doctor of Nursing Practice (DNP) degree and Post-Master’s Certificate in Nursing Education from The Johns Hopkins University. She earned her Master of Science in Nursing (MSN) degree, specializing as an acute care nurse practitioner (ACNP), from Vanderbilt University. Melanie has more than 20 years of experience as a registered nurse and nurse practitioner in adult cardiology and advanced lipid management. She is a part-time faculty member at a top school of nursing where she has taught for more than 15 years.

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