A plaque rupture precipitating acute myocardial infarction or acute coronary syndrome is depicted. Therapeutic interventions dealing with plaque, platelet and thrombus are shown in the blue boxes. ASA, aspirin; IV, intravenous; LMWH, low-molecular-weight heparin; PO, oral; UFH, unfractionated heparin. Adapted with permission from Davies MJ, Thomas AC, Knapman PA, et al: Intramyocardial platelet aggregation in patients with unstable angina suffering sudden ischemic cardiac death. Circulation. 1986 Mar;73(3):418-427.
Read about heart disease in context:
Read more about heart disease:
CURRENT Diagnosis and Treatment: Cardiology, 5e: Chapter 8. Acute Myocardial Infarction
Hurst’s the Heart, 14e. Chapter 108. Women and Heart Disease: An Evolving Saga
Harrison’s Principles of Internal Medicine, 20e. Chapter 268: Non-ST-Segment Elevation Acute Coronary Syndrome (Non-ST-Segment Elevation Myocardial Infarction and Unstable Angina)