| Title of Book and Edition: |
Pharmacotherapy: A Pathophysiologic Approach, 10th Edition |
| Author: |
DiPiro JT, et al, eds. |
| Chapter number/chapter title: |
Chapter 68: Major Depressive Disorder |
| Location of Update in the chapter: |
Treatment, Pharmacologic Therapy |
Content Update
April 28, 2018
Use of Ketamine for Improving Suicidal Ideation: Ketamine is an emerging agent for the rapid treatment of depression. None of the other available antidepressants are effective for rapid relief of suicidal thoughts in patients with depression. Results from a randomized clinical trial suggest that adjunctive use of ketamine was more effective than midazolam in reducing clinically significant suicidal ideation.
