AccessMedicine's Image of the Week: Rectal Mucosal Biopsy Specimen: Shigellosis

From: Currennt Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e

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Rectal mucosal biopsy specimen from a patient with dysentery caused by shigellosis. There is considerable mucosal inflammation caused by infiltration with polymorphonuclear leukocytes and mononuclear cells, as well as substantial damage to surface epithelial cells. However, mucosal architecture is generally preserved with straight, closely adjacent crypts. A crypt microabscess is seen on the right.


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Julie Grishaw, ACNP

Senior Editor, McGraw-Hill Education