Cutaneous manifestations of HIV infection (chronic herpetic gingivostomatitis). Children with AIDS frequently suffer from persistent herpetic infections of the mucous membranes or skin. The gingivostomatitis shown in the above figure would be typical of primary infection in a healthy child. One would then expect recurrences to be considerably milder. By contrast, the child with HIV infection may have recurrent episodes of gingivostomatitis or may develop infection that does not respond at all to acyclovir or related drugs.