COVID-19: The Global Coronavirus Pandemic

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The Centers for Disease Control and Prevention (CDC) and World Health Organization (WHO) continue to search for treatments for preventative methods to control the COVID-19 pandemic. This post is being updated as of September 26, 2021. As of September 26, 2021 there are a total of 231,799,200 global cases with 4,747,625 mortalities. A total of 42,924,281 cases have been reported in the United States, which surpasses the total number of cases reported anywhere else in the world. There have been a total of 687,985 deaths in the United States. In India, there have been 33,652,745 cases with with an associated 446,918 mortalities. In Brazil, there have been a total of 21,351,972 cases with an associated 594,443 mortalities. In the United Kingdom, there have been 7,700,291 cases with an associated 136,528 mortalities. 

The data for overall cases and the data for 28-day cases and mortality varies greatly.  The countries with the highest 28-day mortalities are as follows: United States (50,026); Iran (13,181), India (9,088); Turkey (6,980), and the United Kingdom (3,766).

 The Johns Hopkins map reports updated data on the current case count around the world.

At this time, the global number of vaccinated individuals is reported to be 6,088,102,118.  An estimated 55.3% of the United States population is fully vaccinated. An estimated 64.3% have received one dose.

The mode of transmission of COVID-19 is by respiratory aerosol and is spread from person-to-person. The signs and symptoms associated with COVID-19 are variable and can mimic many other illnesses. According to the CDC,  the following signs and symptoms are associated with COVID-19 at time of illness onset: fever, constant or intermittent (77–98%), cough (46%–82%), myalgia or fatigue (11–52%), and shortness of breath (3-31%). The CDC also noted that while fever was present in only 44% of patients at the time of hospital admission, 89% of patients became febrile during their admission. Other possible symptoms include sore throat, headache, productive cough, nausea, and diarrhea.

Please visit this post for more detailed information on laboratory testing. In addition to the PCR test, the CDC notes other common laboratory abnormalities found in patients with COVID-19. These include: leukopenia (9–25%), leukocytosis (24–30%), lymphopenia (63%), elevated alanine aminotransferase and aspartate aminotransferase levels (37%), thrombocytopenia (36%), and leukopenia (34%).

For all new and updating information concerning the COVID-19 global pandemic, refer to the AccessMedicine COVID-19 Central channel (and "watch" the channel to receive alerts when new and updating information arrives).

Julie Grishaw, ACNP

Senior Editor, McGraw-Hill Education