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Characteristic cytomegalovirus (CMV) inclusion body in biopsy from congenitally infected infant. Classic “owl’s eyes” CMV-associated inclusion body noted in renal biopsy of infant with congenital CMV infection and (unrelated) renal disease. Viral inclusion found within renal tubule (arrow) in infant with high-grade DNAemia, viruria, and sensorineural hearing loss. This infant had no other stigmata of congenital CMV infection.

Source: Kline MW. Rudolph's Pediatrics, 23e; 2018. 

Leah Carton

Associate Editor - Pediatrics, Dermatology, Geriatrics , McGraw Hill