Influenza virus. A: Electron micrograph of influenza virus A/Hong Kong/1/68(H3N2). Note the pleomorphic shapes and glycoprotein projections covering particle surfaces (315,000×). (Courtesy of FA Murphy and EL Palmer.) B: Schematic view of influenza. Virus particles have segmented genomes consisting of seven or eight different RNA molecules, each coated by capsid proteins and forming helical nucleocapsids. Viral glycoproteins (hemagglutinin and neuraminidase) protrude as spikes through the lipid envelope. (Reproduced with permission from Willey JM, Sherwood LM, Woolverton CJ: Prescott, Harley, and Klein’s Microbiology, 7th ed. McGraw Hill, 2008. © McGraw-Hill Education.)
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